Burnettramic acid
WebBurnettramic acid A C41H71NO12 CID 146683156 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ... WebOct 1, 2024 · Burnettramic acid A was recovered in an insoluble fraction at the solvent interface of the aqueous ethyl acetate partition and its purification has been reported elsewhere ( Li et al., 2024 ). For a full isolation scheme, see Figure S2.
Burnettramic acid
Did you know?
WebBurnettramic acid A is active against the Gram positive bacteria, B. subtilis and S. aureus, with IC50 2.3 and 5.9 µg/mL, respectively. Burnettramic acid A is a potent antifungal agent (IC50 0.5 µg/mL and 0.2 µg/mL against C. albicans and S. cerevisiae, respectively). Burnettramic acid A is also active against murine myeloma NS-1 cell line ... WebDec 12, 2024 · Finally, synthetic pyrimidine antimetabolites such as flucytosine interfere with nucleic acid biosynthesis, but resistance via point mutations in the fungal uracil phosphoribosyltransferase or cytosine deaminase enzymes restricts their application to combination therapy [8]. Open in a separate window Figure 1
WebUsnic acid is a major metabolite from a number of lichen and fungal species and is perhaps one of the longest known microbial metabolites, first isolated in 1844. ... Burnettramic acid A. $137.00 - $479.50. View Product Choose Options. Ampicillin Trihydrate, USP $97.00 - $205.00. View Product Choose Options ... WebBurnettramic acid A is active against the Gram positive bacteria, B. subtilis and S. aureus, with IC50 2.3 and 5.9 µg/mL, respectively. Burnettramic acid A is a potent antifungal …
WebJun 1, 2024 · Oleanolic acid (OA), a ubiquitous pentacyclic oleanane-type triterpene isolated from edible and medicinal plants, exhibits a wide spectrum of pharmacological … WebJan 3, 2024 · The recently discovered antibiotic burnettramic acid A (1) and three new congeners, burnettramic acids C-E (2-4), were identified from the co-cultures of two …
WebDec 12, 2024 · The recently discovered antibiotic burnettramic acid A (1) and three new congeners, burnettramic acids C-E (2-4), were identified from the co-cultures of two …
WebABSTRACT: The burnettramic acids are a new class of antibiotics from an Australian fungus Aspergillus burnettii. The rare bolaamphiphilic scaffold consists of β-d-mannose linked to a pyrrolizidinedione unit via a 26-carbon chain. The most abundant metabolite displayed potent in vitro antifungal activity. atar 80Webof its chemical structure based on amino acid sequences. Here, we conducted a phylogenetic analysis ... Ib-A burnettramic acid (24) III-Ac haetoglobosin (19) (A) (B) D-2: leporin (26) D-3 ... atar 92WebBurnettramic acid A aglycone is a fungal metabolite and an aglycone form of burnettramic acid A originally isolated from A. burnettii that has anticancer activity. It is cytotoxic to NS … atar 95asim arifWebByssochlamic Acid is closely related to the mycotoxins rubratoxin B, produced by Penicillium rubrum, and glaucanic acid, isolated from P. glaucum. The reported pharmacology of Byssochlamic Acid is limited to antitumor and phytotoxic activity. Related Products Novobiocic Acid USA Local Phone 360-734-1789 Fax 360-734-0798 … asim arunWebNov 8, 2024 · Figure 1: The clinker pipeline (a) and visualisation of the burnettramic acid biosynthetic gene cluster (Li et al., ... 70 burnettramic acids (Li et al., 2024) is split over three contigs due to fragmented genome assembly, but is readily 71 visualised by our tool (top-most cluster in Figure 1b). Hovering over a locus displays a grey box with ... asim arun ipsWebThe VRPKS-I-6 core gene clustered with burnettramic acid biosynthesis PKS from Aspergillus burnettii and other Aspergillus PKS genes, including A. avenaceus hypothetical protein (KAE8150730) and A ... atar 90